How to Care for Radiation-Sensitive Skin
Skin Care for Chemotherapy
and Radiation Treatment
Evidence-Based Skin Care Guidance During Radiation Therapy
By Mark Brown, RN | Oncology Nurse & Co-Founder of Dermavitality
By Mark Brown, RN | Oncology Nurse &
Co-Founder of Dermavitality

Understanding Radiation-Induced Skin Changes
Radiation therapy is an essential part of cancer treatment, but it can also affect the skin in the treatment area. Many patients experience redness, dryness, itching, tenderness, or peeling as the skin barrier becomes compromised during therapy.
With proper daily care and early intervention, discomfort can often be reduced and the skin better supported throughout treatment. The goal of radiation skin care is to protect the skin barrier, minimize irritation, and promote comfort during recovery.
Common reactions include:
- Redness or darkening similar to a sunburn
- Dry, flaky, or peeling skin
- Tenderness, warmth, or itching
- In some cases, blistering or open sores
Although these effects are common, proper care can reduce discomfort, speed recovery, and protect against more severe irritation.
What Is Radiation-Sensitive Skin (Radiodermatitis)?
Radiation-sensitive skin, also known as radiodermatitis, refers to skin changes that occur during or after radiation therapy. These changes result from damage to rapidly dividing skin cells and weakening of the skin’s natural protective barrier.
Common symptoms include redness, dryness, itching, flaking, tenderness, warmth, and, in some cases, blistering or open areas. Severity varies based on treatment location, dose, and individual skin response

The Emotional Side of Skin Changes
Skin reactions aren’t just physical—they can be emotional. Many patients have told me they feel discouraged when their skin changes or painful when something as simple as wearing clothing becomes difficult.
It’s okay to feel that way. These emotions are part of healing. As nurses, we’ve learned that caring for the skin is also caring for the spirit. Every soothing touch or cooling spray is an act of comfort—a reminder that you deserve ease and care, even in the hardest moments.

What Oncology Care Teams Commonly Recommend
Oncology care teams often recommend gentle, fragrance-free skin care during radiation therapy. Patients are commonly advised to cleanse with mild products, moisturize consistently, avoid irritation, and avoid applying products immediately before treatment sessions unless specifically approved.
Skin care recommendations may vary depending on treatment site and individual skin response, so patients should always follow guidance from their radiation oncology team.
What to Avoid During Radiation Therapy
- Fragranced or scented products
- Alcohol-based lotions or cleansers
- Scrubbing, exfoliating, or rubbing the treated area
- Applying products immediately before radiation sessions
- Hot water, heating pads, or direct sun exposure
- Tight or abrasive clothing over treated skin

Step-by-Step: How to Care for Radiation-Sensitive Skin
Use a mild, fragrance-free cleanser and lukewarm water—never hot. Avoid scrubbing or exfoliating the treatment area. Pat dry softly with a clean towel.
Nurse Tip:
Avoid alcohol-based products near the treatment area, as they may increase irritation.
Begin moisturizing from the first day of treatment. Preventing dryness is easier than repairing it.
Our Radiation Relief Cream delivers a rich yet non-greasy layer of hydration that absorbs quickly and comforts skin throughout the day. Apply it two to three times daily—but not within two hours before radiation sessions.
If your skin feels hot or tight, use a cool, damp compress or spritz the area with Radiation Relief Spray. The lightweight mist delivers immediate cooling comfort without the need for rubbing or pressure.
It’s especially helpful right after treatment, when skin may be too sensitive for touch.
Wear loose, breathable fabrics like cotton or bamboo. Avoid direct sun exposure and skip adhesives or tapes on treated skin.
If hands and feet become red, cracked, or sore—common with certain chemotherapy drugs—apply Hand & Foot Relief Cream. It provides restorative moisture and helps reduce redness and peeling.
Healing skin needs consistency more than complexity. Cleanse gently, moisturize faithfully, protect carefully, and rest often. Small habits done with care make all the difference.
Ingredients Commonly Used for Radiation-Affected Skin
Certain ingredients are commonly included in products formulated for radiation-sensitive skin due to their soothing and hydrating properties.

How Botanical Ingredients Are Used in Supportive Skin Care
Botanical ingredients have long been used in supportive skin care for sensitive or compromised skin. Many patients find comfort in plant-based formulations designed to soothe, hydrate, and support the skin barrier during radiation therapy.
Together, these botanicals form a synergistic blend that cools, hydrates, and restores—free from synthetic fragrance, parabens, and harsh chemicals.
Small Daily Habits That Support Healing
- Stay hydrated. Water supports skin cell repair and overall health.
- Eat nutrient-rich foods. Include antioxidants and healthy fats to nourish from within.
- Avoid friction. Choose soft fabrics and loose clothing.
- Protect from sunlight. Cover treated areas when outdoors.
- Rest and restore. Healing takes energy—listen to your body and allow time to recover.
Healing doesn’t happen overnight, but these small daily actions build strength and comfort over time.

A Nurse’s Perspective on Caring for Radiation-Sensitive Skin
As an oncology nurse, I’ve cared for patients undergoing radiation therapy. Every person brings courage, vulnerability, and a deep desire to feel normal in the middle of an overwhelming experience. What many don’t expect is how significantly radiation affects the skin—and how deeply those changes can influence comfort, confidence, and quality of life.
Redness, itching, tightness, and tenderness are extremely common. As treatment progresses, skin can become dry, inflamed, and hypersensitive to even the slightest touch. To someone on the outside, these reactions may look like simple irritation, but for the person experiencing them, they can feel painful, emotional, and exhausting.

That’s exactly why we created nurse-formulated skincare specifically for radiation-sensitive skin—to provide real relief from the problems treatment causes. Our goal is to make each day a little more comfortable by keeping your skin soothed, nourished, and protected.
Key ingredients that make a difference:
Calendula to calm irritation, reduce redness, and support natural healing
Aloe Vera to cool, hydrate, and ease tightness and tenderness
Shea Butter to restore moisture, strengthen the skin barrier, and prevent further dryness
Nourishing plant oils like jojoba and olive to replenish depleted skin and improve softness
Natural Plant Botanicals to soothe irritated skin
Together, these ingredients work to soothe irritation, restore moisture, calm inflammation, and protect fragile skin—bringing comfort and confidence back to a journey that can often feel anything but comfortable.
How Dermavitality Products Support Your Skin During Chemo and Radiation
Dermavitality offers a range of soothing, plant-based solutions that support skin health during chemo and radiation. Many of these items also make a thoughtful gift for someone going through chemo, helping them feel cared for while managing treatment side effects.
Two Ways to Soothe: Cream and Spray
Our Radiation Relief Cream offers deep, lasting hydration ideal for dry or peeling skin. It absorbs quickly to form a light, protective barrier while delivering botanical nutrients that help calm inflammation and support renewal.
When skin is too tender for touch, the Radiation Relief Spray provides instant, hands-free cooling. A light mist of Aloe, Calendula, Chamomile, and Arnica brings comfort without friction—perfect for post-treatment care or quick relief throughout the day.
Both were created with one goal: to give patients natural, nurse-approved comfort through every step of radiation therapy.


Caring for the Whole Person
Radiation care isn’t just physical—it’s emotional, spiritual, and human. Taking a few moments each day to care for your skin is also caring for your heart. Many patients tell me that using the cream or mist becomes a ritual of hope—a reminder that healing is happening, even when it’s hard to see.
At Dermavitality, we believe that love, faith, and science can work hand in hand. That’s why we continue to create products that honor both your health and your humanity.
You are not alone in this. Every nurse who helped create these formulas understands what you’re facing.

A Gentle, Natural Approach: Nurse-Formulated Care
When creating the Dermavitality line, we wanted more than a product. We wanted a promise—that everything touching the skin of a patient in treatment would be pure, safe, and supportive.
Instead of synthetic chemicals or artificial fragrance, our formulas rely on organic botanicals that nurses and herbalists have trusted for generations. The skin’s natural barrier is already compromised during radiation; it doesn’t need anything harsh. What it needs is calm.
That’s where our Radiation Relief Cream and Radiation Relief Spray come in. Each combines carefully selected plant extracts that soothe inflammation, replenish hydration, and nurture the skin back toward balance.
Conclusion: Supporting Skin Health During Radiation Therapy
Radiation therapy places unique stress on the skin, but gentle daily care can help reduce discomfort and support recovery. Using mild cleansing, consistent moisturizing, avoiding irritation, and following oncology guidance can make a meaningful difference throughout treatment.
Patients should always consult their care team with questions about skin changes or product use during radiation therapy.

How Dermavitality Products Fit Into Radiation Skin Care
Some patients choose nurse-formulated products designed specifically for radiation-affected skin. Brands such as Dermavitality focus on gentle, fragrance-free formulations intended to support comfort and hydration during treatment.
Options may include creams for deep hydration and sprays for hands-free cooling when skin is too tender for touch.
Shop Dermavitality Products
Nutritional & Skin Care Connections
Cancer treatments like chemotherapy and radiation don’t just affect what's inside—they impact your skin in powerful ways. Dryness, flaking, and sensitivity are often made worse by dehydration and poor nourishment.
Final Words from a Nurse
Caring for your skin isn’t just a skincare ritual—it’s essential treatment side effect management. By using gentle cleansing, moisturizing early and often, protecting from sun, and staying vigilant for changes, you can greatly reduce discomfort and support healing.
Stay proactive, be kind to your skin, and reach out whenever you’re unsure. You’ve got this—and we’re here to help.

Final Words from a Nurse

Caring for your skin isn’t just a skincare ritual—it’s essential treatment side effect management. By using gentle cleansing, moisturizing early and often, protecting from sun, and staying vigilant for changes, you can greatly reduce discomfort and support healing.
Stay proactive, be kind to your skin, and reach out whenever you’re unsure. You’ve got this—and we’re here to help.
Disclaimer
This content is for informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician, advanced practice nurse, or other qualified healthcare provider with any questions you may have regarding a medical condition or treatment.





































































