I've been a repeat purchaser for the past 4 years!






Hand-Foot Syndrome Cream for Chemo-Related Skin Problems
HSA/FSA Eligible








Hand-Foot Syndrome Cream for Chemo-Related Skin Problems
See Why Patients, Nurses, Radiation Therapists, and Oncology Teams Recommend Dermavitality.
Trusted by thousands of patients who have found comfort during treatment



Why It Works: Formulated in Three Layers

Step 1. Hydrate
Organic Aloe Vera & Glycerin - Help replenish moisture and leave dry, sensitive skin feeling soft and comfortable.

Step 2. Soothe
Calendula, Roman Chamomile, Oat Oil & Cucumber - Gentle botanicals help comfort delicate skin and reduce the feeling of dryness and tightness.

Step 3. Nourish
Shea Butter, Safflower Oil & Vitamin E - Rich emollients help soften skin, seal in moisture, and maintain the skin’s natural moisture barrier.
Real Relief from Patients Going Through Treatment
Customer Reviews
Overall rating: 4.9 / 5 from 85 reviews.
I have suffered with neuropathy for over 20 years. I never tried the medication suggested so I am a neuropathy “queen” on the subject. I noticed that certain foods triggered it and my stress level. I would use ice and cold compresses to calm the mad internal itch in my hands and feet down. I tried your product and I can truly say it works! First time in 20 years I could actually use a product that I could say “I’m a customer! “ Thank you! I can feel myself again.
Priscilla 5/5 Verified
I find ot very soothing without all the harsh chemicals other lotion s have
Isabelle 5/5 Verified
Great product
Heather 5/5 Verified
Great product. I use daily on hands and feet.
Evelyn 5/5 Verified
It's great on skin for chemo!
Suzanne 5/5 Verified
The hand foot cream is so soothing. I love how my skin feels after using your product.
Karen 5/5 Verified
My husband’s hands and feet were pealing terribly so I started searching for something to help him. I came across this in my research. After reading all through the website, I decided to give it a try. It has made a drastic difference and he is on his second tube. I highly recommend this cream for chemo patients suffering from hand and foot syndrome!
Darla 5/5 Verified
I’ve used the oncology kit and will be using the radiation kit soon . I love all of the products and the customer service is outstanding !
Pamela 5/5 Verified
Good stuff
Lauren 5/5 Verified
The hand/foot cream isn’t as thick and creamy as I expected.
Bonnie 3/5 Verified
It’s the most relief I’ve gotten from the pain.
April 5/5 Verified
Great
Evelyn 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
I have been on chemotherapy for a few months and my hands and feet were cracking open and bleeding. My nails were becoming discolored too. I saw the dermavitality products on social media and ordered the lotion. Within a week to 10 days I noticed a huge difference! They began to heal and look so much better. The company really cares about me as well. One time my order was late so I emailed them. I received a response the next day. I was rushed my order and received it the next day! I am extremely happy and will recommend this product.
Kelly 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
🙂
Colleen 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Love it!
Michele 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Smells good
Jomarie 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
This is such a soothing cream (I am a repeat customer)!
Lindsey 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
I have started treatment with a drug that can cause hand/foot irritation and even blisters. I decided to get ahead of it and went looking for a cream to use everyday. The Hand Foot Calming Cream has done the trick. I just ordered your cream for neuropathy.
Patricia 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
It’s pretty good.
Susan 4/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
I bought the lotion for my daughter, who is undergoing chemotherapy for leukemia. She instantly loved the lasting hydrating effect on her skin and most especially, the wonderful scent. She said it was very calming and reminded her of being in a spa. Her nurses also commented on the pleasant scent and many took note of the product to order it for themselves. Well done Dermavitality!
Tani 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Excellent product, I will be buying this again
Jacob 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
I love this product. It leaves skin feeling so soft. Awesome!
Brenda 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Love this product. It leaves your hands and feet smooth and calmed.
Brenda 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Not only do I use the Hand & Foot Cream, but my husband keeps sneaking it and using it on his hands and feet too...and I’m the cancer patient, not him! 😂 I’ve already finished treatment, but I’m still using these products because they aren’t just for oncology care. They’re simply incredible, clean, natural, and effective skincare that anyone can benefit from. Highly, highly recommend!
Melody 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Soothing on my skin that feels prickly. Scalp cream is a wonderful to use for itching
Rhonda 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
This is a great, nourishing cream!
Lindsey 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Excellent product
Sharon 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
The cream has helped
Kevin 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
I bought this for my dad and he said he noticed the difference right away!
Veronica 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
One of the few products I've ordered that actually does what it promises: it really works! I can feel an immediate improvement and wasn't expecting that. Thank you for creating it. I will be a returning customer.
Rochelle 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Excellent product.
Joan 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
It is a helpful foot cream but I wish it had more nerve relief.
Joseph 3/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
This is the first hand cream I've found that really helps with my cracked hands. It's very soothing and you don't need alot. Definitely would recommend it
Michele 4/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Been using the cream for six months; helps with my neuropathy. Great product!
Robert 4/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Excellent product for side effects of hand foot syndrome.
Joan 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
It's helping a lot with controlling my psoriasis flare up
David 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
This is a fabulous foot cream!
Lindsey 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
My feet were hurting because of the chemo I am getting .Your product gives me the relief that I need to sleep. I will be ordering more. Thank you .
Betty 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
This hand cream is very efficient.
Customer 5/5 Verified
Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin
Why Patients Choose Dermavitality
Formulated specifically for radiation-damaged skin, not a general moisturiser repurposed

Deeply Hydrates & Soothes
Helps comfort dry, itchy, and sensitive skin within minutes of application.

Designed for treatment-sensitive skin
Soothes irritated skin and helps maintain the skin's natural moisture barrier

Made in the USA
Certified US manufacturing to the highest quality standards
Ready to Find Relief?
Join thousands of patients who found comfort during treatment
Free shipping over $50. HSA/FSA accepted