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Hand-Foot Syndrome Cream for Chemo-Related Skin Problems

HSA/FSA Eligible

Sale price$28.95
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Clinical Expertise
Plant-Based
Cruelty-Free
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GMP Certified
Best Lotion/Cream for Hand-Foot Syndrome- Dermavitality  Dermavitality
Hand-Foot Syndrome Cream for Chemo-Related Skin Problems Sale price$28.95

See Why Patients, Nurses, Radiation Therapists, and Oncology Teams Recommend Dermavitality.

Trusted by thousands of patients who have found comfort during treatment

Read More Reviews

Why It Works: Formulated in Three Layers

Step 1. Hydrate

Organic Aloe Vera & Glycerin - Help replenish moisture and leave dry, sensitive skin feeling soft and comfortable.

Step 2. Soothe

Calendula, Roman Chamomile, Oat Oil & Cucumber - Gentle botanicals help comfort delicate skin and reduce the feeling of dryness and tightness.

Step 3. Nourish

Shea Butter, Safflower Oil & Vitamin E - Rich emollients help soften skin, seal in moisture, and maintain the skin’s natural moisture barrier.

Real Relief from Patients Going Through Treatment

Customer Reviews

Overall rating: 4.9 / 5 from 85 reviews.

I have suffered with neuropathy for over 20 years. I never tried the medication suggested so I am a neuropathy “queen” on the subject. I noticed that certain foods triggered it and my stress level. I would use ice and cold compresses to calm the mad internal itch in my hands and feet down. I tried your product and I can truly say it works! First time in 20 years I could actually use a product that I could say “I’m a customer! “ Thank you! I can feel myself again.

Hand-Foot Syndrome Cream for Chemo-Related Skin Problems

My husband’s hands and feet were pealing terribly so I started searching for something to help him. I came across this in my research. After reading all through the website, I decided to give it a try. It has made a drastic difference and he is on his second tube. I highly recommend this cream for chemo patients suffering from hand and foot syndrome!

Hand-Foot Syndrome Cream for Chemo-Related Skin Problems

I’ve used the oncology kit and will be using the radiation kit soon . I love all of the products and the customer service is outstanding !

Hand-Foot Syndrome Cream for Chemo Patients

I have been on chemotherapy for a few months and my hands and feet were cracking open and bleeding. My nails were becoming discolored too. I saw the dermavitality products on social media and ordered the lotion. Within a week to 10 days I noticed a huge difference! They began to heal and look so much better. The company really cares about me as well. One time my order was late so I emailed them. I received a response the next day. I was rushed my order and received it the next day! I am extremely happy and will recommend this product.

Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin

I have started treatment with a drug that can cause hand/foot irritation and even blisters. I decided to get ahead of it and went looking for a cream to use everyday. The Hand Foot Calming Cream has done the trick. I just ordered your cream for neuropathy.

Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin

I bought the lotion for my daughter, who is undergoing chemotherapy for leukemia. She instantly loved the lasting hydrating effect on her skin and most especially, the wonderful scent. She said it was very calming and reminded her of being in a spa. Her nurses also commented on the pleasant scent and many took note of the product to order it for themselves. Well done Dermavitality!

Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin

Not only do I use the Hand & Foot Cream, but my husband keeps sneaking it and using it on his hands and feet too...and I’m the cancer patient, not him! 😂 I’ve already finished treatment, but I’m still using these products because they aren’t just for oncology care. They’re simply incredible, clean, natural, and effective skincare that anyone can benefit from. Highly, highly recommend!

Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin

One of the few products I've ordered that actually does what it promises: it really works! I can feel an immediate improvement and wasn't expecting that. Thank you for creating it. I will be a returning customer.

Hand-Foot Syndrome Cream – Chemo Relief for Dry, Painful Skin

Why Patients Choose Dermavitality

Formulated specifically for radiation-damaged skin, not a general moisturiser repurposed

Green water droplet icon representing hydrating ingredients including organic aloe vera, MSM, and botanical moisturizers that help keep skin soft and comfortable.

Deeply Hydrates & Soothes

Helps comfort dry, itchy, and sensitive skin within minutes of application.

Choose skincare you can feel good about every day. Your skin deserves gentle, clean care. That's why Restore is formulated with nourishing botanicals and free from parabens, sulfates, phthalates, and artificial dyes to help support your skin's natural moisture barrier.

Designed for treatment-sensitive skin

Soothes irritated skin and helps maintain the skin's natural moisture barrier

Made in the USA

Made in the USA

Certified US manufacturing to the highest quality standards

Ready to Find Relief?

Join thousands of patients who found comfort during treatment

Get Relief Now

Free shipping over $50. HSA/FSA accepted