It is the only thing that woks











Neuropathy Cream- Best Cream for Neuropathy in Feet
HSA/FSA Eligible
Plant-Based Relief for Tingling, Burning & Nerve Discomfort
Why Patients Trust Dermavitality for Neuropathy Support
- Experience a comforting blend of Capsicum Fruit Extract, arnica, menthol. peppermint and ginger root, thoughtfully combined to help sensitive hands and feet feel more comfortable throughout the day.
- Designed by an Oncology Nurse
- HSA FSA Eligible some Medicare Advantage plans may also allow eligible OTC benefit
- Formulated for sensitive hands and feet
- Trusted by healthcare professionals and customers nationwide.
- Backed by over 100 verified 5-star reviews.
Description
Patient Experiences
Customers describe a soothing, cooling sensation after applying Dermavitality Neuropathy Relief Cream and often share that it helps them feel more comfortable when their hands and feet are especially sensitive. Many tell us they enjoy the fast-absorbing, non-greasy formula and use it as part of their daily self-care routine.
Some customers also share that they use the cream during chemotherapy, after treatment, or as part of their ongoing skincare routine for sensitive hands and feet.
Who It's Designed For
Dermavitality Neuropathy Relief Cream is designed for people experiencing sensitive, uncomfortable hands and feet, including those dealing with tingling, burning sensations, numbness, or discomfort. It is also a popular choice among individuals undergoing or recovering from cancer treatment.
What Customers Commonly Report
- Cooling, soothing comfort after application.
- Temporary comfort for sensitive hands and feet.
- Fast-absorbing, non-greasy hydration.
- A convenient addition to their daily self-care routine.
- comfortable enough for regular, everyday use.
Benefits
HSA/FSA Eligible – Use qualified HSA/FSA funds where applicable for added convenience.
Capsicum Fruit Extract – A time-honored botanical ingredient selected for our thoughtfully crafted formula to provide warming comfort for sensitive hands and feet.
Cooling Botanical Blend – Peppermint oil, menthol, and camphor deliver an immediate cooling sensation to comfort sensitive skin.
Hydrates & Nourishes – Organic aloe vera and MSM help replenish moisture while leaving skin feeling soft, smooth, and hydrated.
Botanical Skin Support – Arnica, calendula, and ginger root oil work together to soothe, condition, and comfort dry, sensitive skin.
Fast-Absorbing Formula – Non-greasy and lightweight, making it easy to apply throughout the day whenever comfort is needed.
Ingredients
Neuropathy Support Cream Ingredients
- Organic Aloe Barbadensis (Aloe Vera) Leaf Juice
- Glycerin
- Menthol
- Camphor
- Polysorbate 20
- Carbomer
- Capsicum Frutescens Fruit Extract
- Organic Mentha Piperita (Peppermint) Oil
- Lavender (Lavandula Angustifolia) Essential Oil
- Eucalyptus Globulus (Eucalyptus) Oil
- Zingiber Officinale (Ginger) Root Oil
- Arnica Montana (Arnica Flower) Oil
- Calendula Officinalis (Flower) Extract
- MethylSulfonylMethane (MSM)
- Triethanolamine
- Phenoxyethanol, Caprylyl Glycol
- Ethylhexylglycerin
- Hexylene Glycol
How to Use
How to Use
Apply a small amount of Neuropathy Relief Cream to clean, dry skin on the affected hands or feet. Massage gently until fully absorbed. Use as needed throughout the day or as directed by your healthcare provider.
For external use only. Avoid contact with the eyes and other sensitive areas. Wash hands thoroughly after application unless treating your hands. If the product accidentally comes into contact with sensitive areas, rinse thoroughly with cool water. Discontinue use if irritation develops.













Neuropathy Cream- Best Cream for Neuropathy in Feet
See Why Patients, Nurses, Radiation Therapists, and Oncology Teams Recommend Dermavitality.
Trusted by thousands of patients who have found comfort during treatment



Why It Works: Formulated in Three Layers

Step 1. Cool
Peppermint Oil, Menthol & Camphor
Delivers an immediate cooling sensation to comfort sensitive hands and feet.

Step 2. Comfort
Capsicum Fruit Extract, Arnica & Ginger Root
A carefully selected botanical blend designed to provide lasting comfort for sensitive skin.

Step 3. Nourish
Organic Aloe Vera, MSM & Botanical Moisturizers
Hydrates, conditions, and helps keep skin feeling soft, healthy, and comfortable.
Real Relief from Patients Going Through Treatment
Customer Reviews
Overall rating: 4.6 / 5 from 176 reviews.
Helps reduce neuropathy pain in feet.
Vickie 5/5 Verified
Your products are effective. I love using the neuropathy cream the most Aside from my hands and feet, I also use it on my abdominal muscles where i had my surgery.
Jocelyn 5/5
I used it once and it started working on the first day. I felt relieved but my legs and feet were not hurting that bad. I’m waiting to use it the week before my chemo.
Becky 5/5 Verified
It's the only product that I've found so far that gives the neuropathy on my feet any relief.
Carolyn 5/5 Verified
This really helps calm my neuropathy in my feet. Especially at night when it seems to bother me more than the problems with walking.
Karen 5/5 Verified
While going through 6 rounds of chemotherapy (Carboplatin and Taxol), this product was the only one (out of several I tried) that actually worked to keep my neuropathy at bay.
Diane 5/5 Verified
It works instantly!!
Arminda 5/5 Verified
It's my 91 year old mom who's using Dermavitality regularly, and she loves it. Her neuropathy is unrelated to cancer, but this product gives her real relief. I'm grateful for that, and for Dermavitality's well-researched formula that has worked better than anything else she's tried. Thank you!
Kimberlie 5/5 Verified
I have tried many creams and lotions for the chemo induced neuropathy in my feet and none have helped as much as the Neuropathy Support Cream. I use it every night and it works wonderfully for lessening my pain. I love this cream and will continue to buy! Thank you so much 💓
Terri 5/5 Verified
This product has been helping for my feets they feel cool and i can sleep.
Delfina 5/5 Verified
great product
Kim 5/5 Verified
I use it during chemotherapy when the neuropathy flares up the worst. The heavy cooling action works fast to overpower the pain, tingling, and numbness. Getting up and walking during the chemo also helps. Totally recommend this product! So far nothing else I've purchased has compared or worked this good!!
Janette 5/5 Verified
Purchased for my husband with neuropathy feet/legs. He said it's made a huge difference in feet. Walking is without that tingling and pain.
Jayne 5/5 Verified
This gives me relief at night
Gina 5/5 Verified
It helped
Lisa 5/5 Verified
Since going through chemotherapy, I have developed neuropathy in my hands and feet. This is the only cream that has helped with the burning. Once applied to my skin and it penetrates, the painful feeling goes away and allows me to sleep!! The only down side for using on feet is they become super slippery when wet, so be careful when you shower or go in the pool...i learned that day 1 lol. I have given some to others to try and would always recommend.
Elaine 5/5 Verified
I love these products
Angela 5/5 Verified
It helped a little
Andra 3/5 Verified
Originally this cream was purchased for peripheral neuropathy caused by chemo. It actually works for neuropathy caused by nerve compression as well. Thank you.
Elena 5/5 Verified
Excelente lotions they work very good.
Sandra 5/5 Verified
Great product
Gina 5/5 Verified
I have tried nearly all neuropathy, products for the feet. None work well. Many don’t work at all. This works better than most.
Edward 4/5 Verified
Great product and eases the side effects
Stephanie 5/5 Verified
i don"t care for the texture of the cream. I'm also not sure how effective it is. Maybe it would have worked better if I had started using it when I first began chemo to prevent the neuropathy.
Barbara 3/5 Verified
I continue to get relief while doing my chemo treatments! Strongly recommend!
Tammy 5/5 Verified
This is the only product that helps my disabled, adult daughter, that suffers from severe neuropathy in her feet. It allows her to sleep at night and not have the burning in her feet.
Bruce 5/5 Verified
I have diabetic neuropathy and spinal senosis nerve pain and it feels really good on my feet and legs. Thanks for a great product!
Dolores 5/5 Verified
I have chemo induced neuropathy and if you google it, it says there is no cure, I saw this online and it seems to be helping, my feet feel a tiny bit better, only been using it for about a week, plus I am doing laser therapy with my chiropractor.
Linda 5/5 Verified
Really is helpful for the neuropathic discomfort. I use two times daily.
Marjorie 5/5 Verified
I started out using the face cream during chemo as my skin was suffering so badly with dryness and blotchiness, which I knew was a side effect. It has been a lifesaver and the only cream I’ll use on my face. I then try the neuropathy cream for my feet and I have to tell you it really works. It doesn’t completely take it away, but it certainly eases the pins and needles and numbness. I’m so grateful to have found your products.
Kathy 5/5 Verified
This cream is almost magical. Suffering neuropathy bad, I got out of bed and applied to both feet. It helps me to put either footies or compression socks on after applying. Got back in bed and within 10 minutes it was like I almost couldn't feel my feet much less the pain. It hurt to even walk on carpet daily. I made copies of the flier that comes with order and took to my infusion center and several people ordered it and was very pleased how well it worked. It does seem to be sticky at first, if used on hands, but once it dries good, less than 5 minutes, you don't know it's there. Just keep hands away from eyes and mouth. Lips will actually get numb if you touch them. Try it. You will never use anything else. Worth every penny. 😊
Carol 5/5
Helps with my neuropathy. It really works.
Racquel 5/5 Verified
I use the cream for neuropathy in my feet. It helps relax the tingling. It hasn’t “cured” my neuropathy, but it does give me some short term relief. It’s the only product that has done that.
Carolyn 4/5 Verified
Great product. Helps with my joint pain.
Evelyn 5/5 Verified
good product
Lisa 5/5 Verified
I only brought the simpler to try. It’s a little expensive for me.
Jackie 5/5 Verified
I use your scalp spray and my hair and scalp are in excellent condition. Also on my second tube of neuropathy cream which I use daily on my feet and legs. Gives me a lot of relief and soothes the discomfort.
Janet 5/5 Verified
The calming cream makes a difference in how my hands and feet feel during my acupressure massages to help with neuropathy. I also received gift of the Oncology Body Lotion and it helps to keep my skin hydrated before and after Chemo.
Debbie 5/5 Verified
Great product.
Evelyn 5/5 Verified
Why Patients Choose Dermavitality
Formulated specifically for radiation-damaged skin, not a general moisturiser repurposed

Deeply Hydrates & Soothes
Helps comfort dry, itchy, and sensitive skin within minutes of application.

Designed for treatment-sensitive skin
Soothes irritated skin and helps maintain the skin's natural moisture barrier

Made in the USA
Certified US manufacturing to the highest quality standards
Frequently Asked Questions
What is Dermavitality Neuropathy Support Cream?
Dermavitality Neuropathy Support Cream is recognized as one of the best nerve pain cream available. This natural, topical formula is designed to support individuals experiencing neuropathy symptoms by combining plant-based ingredients to soothe discomfort, reduce inflammation, and provide relief to areas affected by nerve-related pain.
How does Neuropathy Support Cream work?
The cream combines natural anti-inflammatory and soothing ingredients that penetrate the skin to help alleviate symptoms such as tingling, numbness, and discomfort associated with neuropathy. It helps by supporting healthy circulation and calming sensitive nerve endings.
What are the main ingredients in Neuropathy Support Cream?
Our formula includes ingredients like arnica, aloe vera, turmeric, and menthol, known for their anti-inflammatory and pain-relieving properties. These natural ingredients work together to support your body’s natural healing processes.
How often should I apply the cream?
For best results, apply 2–3 times daily or as needed. Many customers choose to apply the cream in the evening or before bedtime as part of their nightly routine to help comfort sensitive hands and feet before sleep.
Can I use this cream alongside my current medication?
Neuropathy Support Cream is a topical solution with natural ingredients. However, if you are taking prescription medications or have specific health concerns, it’s recommended to consult your healthcare provider before use.
How long does it take to feel relief?
Results may vary, but many users report noticeable relief within a few minutes to a few days of consistent use. Regular application can help maintain comfort and reduce symptoms over time.
Is the Neuropathy Support Cream safe for sensitive skin?
Yes, the cream is formulated to be gentle and suitable for most skin types, including sensitive skin. If you have a known allergy to any ingredients, consult the product label and test a small amount on your skin first.
Can this cream help with other types of pain?
While designed for neuropathy, the cream may provide relief for muscle aches, joint pain, and other discomforts due to its soothing and anti-inflammatory properties. Consult with a healthcare professional to determine if it’s suitable for your specific condition.
How long does a tube last?
Each tube contains enough product for several weeks of regular use, depending on the application frequency and amount used. Following the recommended application can help maximize the product’s duration.
Is Neuropathy Support Cream cruelty-free?
Yes, Dermavitality is committed to cruelty-free practices. Our products are not tested on animals, and we strive to source sustainable, plant-based ingredients.
Can I purchase Neuropathy Support Cream in stores?
Currently, Neuropathy Support Cream is available for purchase exclusively online through the Dermavitality website, ensuring you receive a fresh, high-quality product directly from us.
What is your return policy?
If you’re not fully satisfied with your purchase, please reach out to our customer service team within 30 days of receiving your order. We are happy to assist with returns and exchanges to ensure your satisfaction with Dermavitality.
What makes Dermavitality Neuropathy Relief Cream different?
Dermavitality Neuropathy Relief Cream was designed by an Oncology Nurse using a carefully selected blend of botanical ingredients, including Capsicum Fruit Extract, aloe vera, MSM, arnica, peppermint oil, and menthol. The fast-absorbing, non-greasy formula is designed to provide soothing comfort for sensitive hands and feet.
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