I'm currently undergoing breast radiation treatment. I've followed the advice given and put the spray in the fridge. It's so soothing after radiation and it cools that immediate burning. The lotion is light and easy to use. It moisturizes great and controls the itching. Wonderful product. It's also very affordable.












Calendula Spray & Cream for Radiation Therapy Patients
HSA/FSA Eligible
Your Skin Is Going Through Treatment Too.
Radiation therapy can leave skin feeling dry, tight, itchy, sensitive, and increasingly uncomfortable as treatment progresses. Your daily skincare routine should be gentle, simple, and designed around what your skin is experiencing.
Dermavitality's Radiation Spray & Cream Bundle was created as a two-step botanical skincare system for patients undergoing radiation therapy. The no-touch Radiation Relief Spray delivers lightweight hydration and botanical comfort when skin is too sensitive to rub, while helping prepare the skin for the rich, lasting moisture of the Radiation Relief Cream. Together, they create a simple daily routine for keeping treatment-area skin comfortable and cared for.
Why This Two-Step System Works
💦 Step 1. No-Touch Botanical Comfort
The Radiation Relief Spray delivers a lightweight, refreshing mist with aloe vera, calendula, arnica, chamomile, and cucumber to comfort dry, sensitive skin without rubbing. The no-touch application helps make it easier to begin your skincare routine when treatment-area skin feels especially tender.
🌿 Step 2. Deep Hydration & Barrier Support
Once the spray has absorbed, apply the Radiation Relief Cream to replenish moisture with organic aloe vera, calendula, shea butter, jojoba oil, and vitamin E, helping support the skin's natural moisture barrier.
Why Patients Trust Dermavitality
✓ Designed by an Oncology Nurse
✓ Created with a Breast Cancer Survivor
✓ Used in hundreds of oncology centers
✓ Trusted by patients and caregivers
⭐⭐⭐⭐⭐ 463 Verified Reviews
Description
The Complete Radiation Skincare System
Designed by an Oncology Nurse and a Breast Cancer Survivor
A two-step approach to help comfort, hydrate, and support radiation-sensitive skin during and after treatment.
Cooling Relief When You Need It Most
For an extra cooling sensation, refrigerate the Radiation Relief Spray before use. Formulated with organic Calendula, Arnica, Aloe Vera, and Oat Straw Extract, it helps soothe and comfort radiation-sensitive skin. Spray first to help make moisturizing more comfortable, then follow with the Radiation Relief Cream to lock in lasting hydration.
Step 2: Deeply Hydrate
After using the cooling spray, apply the Radiation Relief Cream to replenish moisture and help support the skin's protective barrier. Powered by organic calendula, botanical hyaluronic acid, aloe vera, and shea butter, the rich cream helps keep dry, sensitive skin hydrated and comfortable throughout treatment.
Benefits
Why This System Is Different
Most radiation patients are given a single cream and told to moisturize.
But as treatment progresses, skin often becomes increasingly dry, tender, and sensitive. For many patients, even applying moisturizer can become uncomfortable.
Spray First. Then Moisturize.
Our Radiation Relief Spray can be refrigerated for cooling comfort and features Organic Calendula, Arnica, Aloe Vera, Oatstraw Extract, Chamomile, and Lavender.
This first step helps calm and hydrate sensitive skin, making it easier and more comfortable to apply moisturizer.
Lock In Moisture
Once skin is prepared, Radiation Relief Cream delivers rich hydration with Organic Calendula, Botanical Hyaluronic Acid, Shea Butter, Aloe Vera, and Jojoba Oil to help replenish moisture and support the skin barrier.
A Complete Comfort + Hydration Routine
Most products focus only on moisturizing.
Dermavitality's two-step system helps patients cool, comfort, hydrate, and moisturize throughout treatment..
Ingredients
Radiation Relief Spray Ingredients
- Organic Aloe Leaf Juice (Aloe Barbadensis)
- Orange Blossom Water (Citrus Aurantium)
- Organic Calendula Flower Extract (Calendula Officinalis)
- Arnica Flower Extract (Arnica Montana)
- Roman Chamomile Oil (Anthemis Nobilis)
- Lavender Flower Oil (Lavandula).
Radiation Relief Cream Ingredients
- Organic Aloe Vera Leaf Juice
- Sunflower Seed Oil
- Organic Calendula Oil
- Emulsifying Wax (Isopropyl Palmitate, Glyceryl Stearate, Cetyl Alcohol, Stearic Acid)
- Glycerin
- Botanical Hyaluronic Acid
- Shea Butter
- Organic Jojoba Oil
- Lavandin Oil, Panthenol (Vitamin B5)
- Vitamin E Acetate
- Sea Water Extract
- Organic Green Tea Extract
- Yarrow Extract
- Irish Moss Extract
- Spirulina Extract
- Organic Gotu Kola Extract
- Horsetail Extract
- Wild Geranium Extract
- Dandelion Extract
- Xanthan Gum
- Phenoxyethanol.
How to Use
Radiation Relief Spray
- Apply the spray approximately 5 minutes before using the Radiation Relief Cream to help calm discomfort prior to moisturizing.
- For additional cooling comfort, the spray may be stored in the refrigerator.
- Discontinue use if skin ulceration develops and notify your healthcare provider.
- May be used for up to 6 weeks after the final radiation treatment.
Radiation Relief Cream
For best results, begin using the cream one week prior to the start of radiation therapy.
- Apply 3–4 times daily or as often as desired.
- Do not apply within one hour prior to radiation treatment.
- Discontinue use if skin ulceration develops and notify your healthcare provider.
- May be used for up to 6 weeks after the final treatment.














Calendula Spray & Cream for Radiation Therapy Patients
See Why Patients, Nurses, Radiation Therapists, and Oncology Teams Recommend Dermavitality.
Trusted by thousands of patients who have found comfort during treatment



Why It Works: Formulated in Three Layers

Step 1. Refresh
No-touch botanical hydration with aloe vera, calendula, arnica, and chamomile comforts sensitive skin.

Step 2. Comfort
The lightweight cooling spray kept in the refrigerator soothes and prepares skin before applying the rich Radiation Relief Cream.

Step 3. Restore
Deep hydration from aloe vera, calendula, shea butter, jojoba oil, and vitamin E supports the skin's natural moisture barrier, helping to soothe and support your skin during radiation therapy.
Real Relief from Patients Going Through Treatment
Customer Reviews
Overall rating: 4.9 / 5 from 472 reviews.
I was recommended the Dermavitality Radiation Cream by my radiation oncologist. I was given samples and found the cream to be very beneficial for treating the aftereffects of radiation. It made a great difference in how my skin healed and definitely lessened the dry skin and itching associated with the radiation. I ordered two six-ounce bottles of the product in the lavender scent which I found very calming. However, the cream comes in both scented or non-scented options, which is good for those who have allergies. I would highly recommend this product to anyone who must undergo radiation treatment. It is a great product!
Sharon 5/5 Verified
Fabulous, pure healing products. I am using them long after treatment, and will continue!
Jennifer 5/5 Verified
I am so sensitive to all creams and even adhesive in bandage tapes so the samples were essential so i can see if i am sensitive. TO MY WONDERFUL surprise!! , i used the radiation cream and spray during radiation treatment . My experience with the product has been great . It was like my skin was yearning and absorbing it, so soothing not to heavy scent( just perfect lite and pleasant). My red excoriations and oozing areas felt so much better and healed well with the cream on my chest . Amazingly enough as i started to use and mention to all around me during my appointments or treatments , everyone seemed to ask bout the ingredients and wanted to try it for their specific skin concerns for self or family etc. In my family it is helping with other skin challenges and they all love the creams gentleness, not heavy scent and soothing emollient feel on the skin to relieve that Raw feel when skin is not happy for whatever reason . The neuropathy cream for my feet and hands is also a good comforting help . During these challenging treatment times and any chronic situation skin gets so dry and older looking on the face . I love the face serum smells great lite and so moisturizing that lasts the whole day not like others that i have used in my experience and i had to reapply several times a day . My fave is the radiation spray esp after radiation until get home to put cream it was cool and comforting or any time skin felt tight and unhappy even after finished radiation and restarted chemo still using both spray and cream helping in healing the skin. My fave is the radiation spray especially after the treatment was such calming and healing feeling until i got home to put Cool ( keep refridgerated !!)cream on it . Even after finished radiation and restarted chemo still using both spray and cream helping in healing the skin . thank you again God Bless. Hannan
Hannan 5/5 Verified
It feels good on the skin. I got the unscented since I'm not sure if it would be irritating my skin once I start radiation therapy.
Kateena 4/5 Verified
Absolutely love the lotions and radiation spray. I had 16 rounds of radiation and have not encountered any skin issues. Thanks for making such a great product! LR
L 5/5 Verified
I love the spray. It works efficiently for me and it makes my sore smells good and stop itching, however the ointment or lotion does not do anything for me, use it alone or combine with the spray. I will order more spray when I need it. Thank you, Avau
Avau 4/5 Verified
Lotion and spray relieve the burn from radiation.
Jaime 5/5 Verified
I have been using Deravitality products since I started my chemo treatmen and I enjoy how them very much, now I am doing radiation and started using radiation spray and lotion to help mitigate any issues
Mercedes 5/5 Verified
Been using for the past 2 weeks and so far they have been amazing.
Miguel 5/5 Verified
Love the products
Paige 5/5 Verified
My husband used the cream after 35 radiation treatments. The doctor gave us the cream at the end of this, but I wish we could’ve had it all along. It was very soothing and helped in the healing process.
Ellie 5/5 Verified
Both Creme and spray are very soothing. I apply 4x a day and would highly recommend it.
Tamara 5/5 Verified
Very soothing for my radiation spot...
Anne 5/5 Verified
Im using this all over my body, feels really good.
Kerina 5/5 Verified
I love the radiation spray and cream.
L 5/5 Verified
This product is very soothing to skin burnt by radiation. Much more effective than other samples provided by the radiation department. I love the scent and the 6 oz. size has lasted three weeks and I still have nearly a third of it left. I highly recommend this product.
Heather 5/5 Verified
My Radiation cream worked really great and I really appreciated your help with my problem when I ordered and took great care to correct my account i will order again if needed but at this point I’m in remission 🙏🙏🙋♀️💕
Carol 5/5 Verified
Radiation Burn Cream- Best Cream for Radiation Burns During Therapy
Amazing after care
Tyler 5/5 Verified
Received sample paks from the Dr. during the later days of my Radiation - removal of 3ea squamous cells from my scalp. It reduced the pain and kept my scalp moist so there was little to no pain from frowning, raising my eyebrows, etc....It also helped in the overall removal of the (Lack of other words and/or description) "slime" that formed during the months it took for my scalp to heal.
Vern 5/5 Verified
I really like how soothing this product is to the area affected by the radiation. It's not greasy at all, which is a huge plus for me. I would recommend this to anyone going through radiation. I didn't have chemo, so I can only comment how great the cream & spray is for the radiation burns. Thank you guys! So glad I found this product!
Caroline 5/5 Verified
This set helped me immensely with the radiation burn, keeping my skin hydrated... and it smells wonderful!
Stacie 5/5 Verified
Love & like your products
Jacqueline 5/5 Verified
So far so good! Wish the size was a bit bigger because I use a lot at a time.
Deanna 4/5 Verified
I ran out of the product I used during past radiation treatment. I found that one to be great for sunburn as well as radiation burn, so in searching for RADX, which I could not find, I found your great, natural product. I love it. Smells lovely and works well!
Shanda 5/5 Verified
It was a quick delivery.
Cheryl 5/5 Verified
I am 5 treatments of radiation with 15 to go. The radiation cream and spray are wonderful! Not greasy and the lavender fragrance is light. Feels good as a hand cream too. Spray is great as it helps for the hard to reach areas.
Cynthia 5/5
I’m only 4 treatments in. So far so good. I hope my skin still looks the same after treatment 20
Kathy 5/5 Verified
A penas tengo unos días usándola. No puedo dar una opinión.
Claudia 3/5 Verified
This product is amazing and it calms my hands almost immediately. I am very impressed. Thank you Sandra
Sandra 5/5 Verified
The radiation cream and spray were wonderful. I keep the spray in the frig. I tolerated the radiation pretty good with minimal peeling. But the area under my armpit and on the side did discolor and was sensitive. The lotion and spray worked wonders. I have been told that the radiation continues to cook for months and I have kept using the lotion to this day. Totally endorse the lotion.
Peggy 5/5 Verified
I bought the lotion and spray for my aunt who is going through radiation therapy for a sarcoma in her thigh and she tells me she likes the way it feels and works on her skin and she mentioned how she liked the lavender scent. She is 1/2 way through her 6 weeks of daily radiation treatments now. Also, Mark was a great resource for me answering any questions and or concerns I had , he even called me personally to help with my order. Great company and great products. Would highly recommend them. Thanks Mark for all you do.
Bonnie 5/5 Verified
Radiation Burn Cream & Calendula Spray for Radiation Therapy Patients
I really love the products,very light and non greasy.My skin feels smoother and moisturized.I highly recommend these to cancer patients like me whos currently doing some treatments.
Aisie 5/5 Verified
I really like the cream
Martha 5/5 Verified
Radiation Burn Cream- Best Cream for Radiation Burns During Therapy
I have shared my experience with the New York Proton Center. Your product helped so much during my recovery. Thank you.
Lenore 5/5 Verified
Radiation Relief Spray for Skin- Soothe & Repair Radiation Damage
This has really helped my dryness and redness. I use it on my whole body! Lifesaver for sure during chemo!
Tina 5/5 Verified
I absolutely love the radiation spray and cream. The products contains helpful ingredients to sooth and calm irritated skin from radiation. The spray has been particularly helpful when the skin is itchy, and the cream has the perfect soothing coolness.
Elizabeth 5/5 Verified
It made the aftereffects of proton radiation much more bearable. When the skin is so sensitive to touch, the spray was incredibly helpful. Thank you for your wonderful product.
Lenore 5/5 Verified
Radiation Relief Spray for Skin- Soothe & Repair Radiation Damage
Helped tremendously with eczema flare up!
Audrey 5/5 Verified
Radiation Relief Spray for Skin- Soothe & Repair Radiation Damage
Love this cream! It helped me so much after radiation. Great moisturizer, not greasy, fast absorption. Even used it on my chest just below my neck. The skin was leather looking and ruff from too much sun over the years. Softened it right up again. The spray is amazing for your back. No matter what angle you hold the bottle it sprays areas you can't reach. Definitely reccomend these
Candi 5/5 Verified
Why Patients Choose Dermavitality
Formulated specifically for radiation-damaged skin, not a general moisturiser repurposed

Deeply Hydrates & Soothes
Helps comfort dry, itchy, and sensitive skin within minutes of application.

Designed for treatment-sensitive skin
Soothes irritated skin and helps maintain the skin's natural moisture barrier

Made in the USA
Certified US manufacturing to the highest quality standards
Frequently Asked Questions
What is calendula spray used for?
Calendula spray soothes, cools, and calms skin that has become red, itchy, or irritated-especially after radiation therapy. It provides instant relief while helping to reduce inflammation and support skin healing. The blend of organic calendula, aloe, arnica, and chamomile within the spray will help nourish and hydrate sensitive skin, making it perfect for use prior to radiation cream or anytime your skin feels warm or uncomfortable.
Is calendula spray safe for pregnancy?
Most types of skin will be safe with calendula spray made from natural and organic ingredients like aloe, chamomile, and calendula. But since each pregnancy may be different, it is best to ask your healthcare provider first. Many people prefer this as a natural way to soothe sensitive or irritated skin throughout a pregnancy due to it being paraben-, sulfate-, and harsh chemical-free.
How does one make calendula spray?
A simple calendula spray can be made by steeping dried calendula petals in hot water or aloe juice, then cooling and straining. Added to this, you can include soothing ingredients such as arnica, chamomile, and lavender essential oil. Dermavitality takes this one step further with its Organic Calendula Spray, offering organic plant extracts and antioxidant-rich botanicals to provide increased relief and healing support for the skin.
Is calendula safe to use on skin?
Yes, calendula is known to be non-irritating and safe for the skin. For centuries, it has been used to soothe irritation, reduce redness, and facilitate the healing process. Calendula is derived from the marigold flower and embodies within it natural compounds that help in soothing inflammation, thus supporting the repair of impaired or sensitive skin. That is why it is commonly applied in creams and sprays for patients undergoing radiation therapy or experiencing dry and irritated skin.
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